Clinical features and drug sensitivity pattern of Klebsiella pneumoniae sepsis: A descriptive study in a level 2 neonatal care unit in India

Objectives: To study the signs and symptoms of neonatal sepsis caused by Klebsiella pneumoniae and the antibiotic sensitivity pattern of Klebsiella pneumoniae in a level 2 neonatal unit in India. Method : This descriptive study was conducted with neonates who were admitted in Sick Newborn Care Unit (level 2 neonatal care unit) and whose blood culture showed growth of Klebsiella pneumoniae in a study period of 1 year. The data was entered into a register and presented by descriptive statistics. Results: Forty eight neonates were included in the study. Predominant presenting symptoms were abdominal distension (75%), petechiae, purpura (62.5%) and sclerema (50%). Klebsiella pneumoniae was highly sensitive to tigecycline and meropenem. Conclusions: Predominant presenting symptoms of neonatal sepsis caused by Klebsiella pneumoniae were abdominal distension, petechiae, purpura and early sclerema. Klebsiella pneumoniae was highly sensitive to tigecycline and meropenem. Sri Lanka Journal of Child Health , 2017; 46 (3): 259-261