Open AccessPrevalence of Helicobacter pylori in benign gastric ulcers in a cohort of Sri Lankan patients
Author(s) -
Sulochana Wijetunge,
Rasika B Kotakadeniya,
F. Noordeen,
S.M. Buharideen,
Bandula Samarasinghe,
Arinda Dharmapala,
K. B. Galketiya
Publication year - 2016
Publication title -
ceylon medical journal
Language(s) - English
Resource type - Journals
eISSN - 2386-1274
pISSN - 0009-0875
DOI - 10.4038/cmj.v60i4.8224
Subject(s) - medicine , medical journal , ceylon , sri lanka , helicobacter pylori , family medicine , editorial board , alternative medicine , public health , relevance (law) , traditional medicine , library science , south asia , pathology , ancient history , law , political science , computer science , history
Helicobacter pylori prevalence is decreasing globally and prevalence of non H. pylori gastric ulcers is increasing. The following study was conducted to assess the prevalence of H. pylori in benign gastric ulcers in a sample of Sri Lankan patients. This was a cross-sectional study of 59 dyspeptic patients with benign gastric ulcers. Multiple endoscopic gastric biopsies were obtained and histology, immunohistochemistry and polymerase chain reaction were performed for H. pylori detection. An immunochromatography assay was performed to detect blood anti H. pylori antibodies. Four (6.8%) were positive for H. pylori. Therefore, it is likely that most benign gastric ulcers are of non-H. pylori aetiology.
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