Open AccessChronic hypernatraemia due to osmoreceptor dysfunction
Author(s) -
W M H S Chandrasekara,
S. K. Thondam,
MD Penney,
Lakdasa Premawardhana
Publication year - 2008
Publication title -
ceylon medical journal
Language(s) - English
Resource type - Journals
eISSN - 2386-1274
pISSN - 0009-0875
DOI - 10.4038/cmj.v53i3.258
Subject(s) - medicine , medical journal , ceylon , alternative medicine , family medicine , medical education , pathology , computer science , programming language
Plasma osmolality is regulated by the interaction of the kidneys, arginine vasopressin (AVP), and thirst – the last two being stimulated by hypothalamic osmoreceptor signals. Osmoreceptor dysfunction may cause hypernatraemia, hyperviscosity and considerable morbidity, and may be associated with other endocrine dysfunction [1,2]. We report two patients with chronic hypernatraemia and osmoreceptor dysfunction.
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