Treatment of Alcohol Withdrawal Syndrome: Phenobarbital vs CIWA-Ar Protocol | Zendy

William P. Tidwell | Zendy; Tonya L. Thomas | Zendy; Jonathon D. Pouliot | Zendy; Angelo E. Caico | Zendy; Angus J. Webber | Zendy

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Treatment of Alcohol Withdrawal Syndrome: Phenobarbital vs CIWA-Ar Protocol

Author(s) -

William P. Tidwell,

Tonya L. Thomas,

Jonathon D. Pouliot,

Angelo E. Caico,

Angus J. Webber

Publication year - 2018

Publication title -

american journal of critical care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.592

H-Index - 81

eISSN - 1937-710X

pISSN - 1062-3264

DOI - 10.4037/ajcc2018745

Subject(s) - medicine , alcohol withdrawal syndrome , phenobarbital , intensive care unit , mechanical ventilation , anesthesia , benzodiazepine , incidence (geometry) , emergency medicine , alcohol , biochemistry , chemistry , physics , receptor , optics

Benzodiazepine-based therapy for alcohol withdrawal is associated with agitation and respiratory depression. Treatment can be complicated by a need for adjunctive therapy to control these symptoms and in patients requiring mechanical ventilation. Strong evidence for the effectiveness of alternative treatment modalities is lacking, despite the availability of promising pharmacological agents such as phenobarbital.

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