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Studies on Genomic DNA Stability in Aluminium-Maltolate Treated Aged New Zealand Rabbit: Relevance to the Alzheimer’s Animal Model
Author(s) -
Magisetty Obulesu
Publication year - 2009
Publication title -
journal of clinical medicine research
Language(s) - English
Resource type - Journals
eISSN - 1918-3011
pISSN - 1918-3003
DOI - 10.4021/jocmr2009.09.1265
Subject(s) - ethidium bromide , dna damage , agarose gel electrophoresis , disease , comet assay , medicine , alzheimer's disease , dna , hippocampus , microbiology and biotechnology , pathology , biology , biochemistry
Alzheimers disease (AD) is a devastative neurodegenerative disorder. Lack of substantial animal model that can unravel molecular underpinnings has been a major lacuna which limited the understanding of the etiology of the disease in turn limiting the employment of potential therapeutic strategies to combat the disease for a few decades. Our studies for the first time provided substantial animal model and tattered the etiology of the disease at a molecular level.

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