Polymyxins and Doripenem Combination Against KPC-Producing Klebsiella pneumoniae | Zendy

Lee | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Polymyxins and Doripenem Combination Against KPC-Producing Klebsiella pneumoniae

Author(s) -

Lee

Publication year - 2013

Publication title -

journal of clinical medicine research

Language(s) - English

Resource type - Journals

eISSN - 1918-3011

pISSN - 1918-3003

DOI - 10.4021/jocmr1220w

Subject(s) - doripenem , colistin , polymyxin , microbiology and biotechnology , polymyxin b , klebsiella pneumoniae , medicine , antibiotics , carbapenem , minimum inhibitory concentration , pharmacology , biology , antibiotic resistance , escherichia coli , meropenem , biochemistry , gene

Most KPC-producing organisms have maintained susceptibility to polymyxins; however, development of resistance to polymyxins has been increasingly reported. One potential treatment modality is to optimize the use of combination therapy. Therefore, we evaluated the in vitro activity of doripenem, colistin sulfate, polymyxin B alone and in combination against KPC- producing K. pneumoniae.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research