Comparison of the Stability of Poly-��-Glutamate Hydrogels Prepared by UV and ��-Ray Irradiation | Zendy

SangJoon Park | Zendy; Hiroshi Uyama | Zendy; Misun Kwak | Zendy; Monn-Hee Sung | Zendy

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Comparison of the Stability of Poly-��-Glutamate Hydrogels Prepared by UV and ��-Ray Irradiation

Author(s) -

SangJoon Park,

Hiroshi Uyama,

Misun Kwak,

Monn-Hee Sung

Publication year - 2019

Publication title -

journal of microbiology and biotechnology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.601

H-Index - 64

eISSN - 1738-8872

pISSN - 1017-7825

DOI - 10.4014/jmb.1812.12018

Subject(s) - self healing hydrogels , irradiation , biodegradation , polymer chemistry , chemical engineering , chemistry , materials science , nuclear chemistry , organic chemistry , physics , nuclear physics , engineering

Poly-γ-glutamate (γ-PGA) has various applications due to its desirable characteristics in terms of safety and biodegradability. Previous studies have been conducted on γ-PGA hydrogels produced by γ-ray irradiation, but these hydrogels have proved unstable in solutions. This study was conducted to enable the γ-PGA hydrogel to maintain a stable form in solutions. The γ-PGA mixture for UV-irradiation was prepared with a cross-linker (N,N,N-trimethyl-3-[(2- methylacryloyl)amino]propan-1-aminium). Both γ-PGA hydrogels' characteristics, including stability in solutions, were examined. The UV-irradiated γ-PGA hydrogel maintained a stable form during the nine weeks of the study, but the γ-ray irradiated hydrogel dissolved after one week.

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