Open AccessDiagnostic Value of Cerebrospinal Fluid Level of Carcinoembryonic Antigen in Patients with Leptomeningeal Carcinomatous Metastasis
Author(s) -
Sung Jin Kang,
Kwang S. Kim,
Yoon Suk Ha,
So Young Huh,
Ji Hyun Lee,
Jong Kuk Kim,
Min Jeong Kim
Publication year - 2010
Publication title -
journal of clinical neurology/the journal of clinical neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.208
H-Index - 45
eISSN - 2005-5013
pISSN - 1738-6586
DOI - 10.3988/jcn.2010.6.1.33
Subject(s) - carcinoembryonic antigen , medicine , leptomeninges , cerebrospinal fluid , metastasis , pathology , brain metastasis , cancer , central nervous system
Multifocal seeding of the leptomeninges by malignant cells, which is usually referred to as leptomeningeal carcinomatous metastasis, produces substantial morbidity and mortality. The diagnosis of leptomeningeal metastasis is usually established by cerebrospinal fluid (CSF) investigation, including cytology, cell counts, protein, glucose, and a tumor marker such as carcinoembryonic antigen (CEA). This study examined the diagnostic value of CEA in the CSF.