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Striopallidodentate Calcification and Progressive Supranuclear Palsy-Like Phenotype in a Patient with Idiopathic Hypoparathyroidism
Author(s) -
TaeWon Kim,
InSeok Park,
SungHoon Kim,
Kwang-Soo Lee,
Yeong-In Kim,
JoongSeok Kim
Publication year - 2007
Publication title -
journal of clinical neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.208
H-Index - 45
eISSN - 2005-5013
pISSN - 1738-6586
DOI - 10.3988/jcn.2007.3.1.57
Subject(s) - progressive supranuclear palsy , hypoparathyroidism , medicine , parkinsonism , basal ganglia , calcification , pathology , dementia , white matter , radiology , magnetic resonance imaging , atrophy , disease , central nervous system
We present a 77-year-old woman with levodopa-nonresponsive parkinsonism, dementia, and supranuclear gaze palsy on vertical and horizontal gaze. Laboratory findings were consistent with idiopathic hypoparathyroidism, and brain computed tomography showed extensive bilateral calcifications of the basal ganglia, centrum semiovale, dentate nuclei, and cerebellar white matter. These results illustrate that striopallidodentate calcification due to hypoparathyroidism may present with symptoms mimicking progressive supranuclear palsy.

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