The Ideal Synthetic Method Aimed at the Leads for an a2-Blocker, an Inhibitor of Blood Platelet Aggregation, and an Anti-osteoporosis Agent | Zendy

Masanori Somei | Zendy; Takako Iwaki | Zendy; Fumio Yamada | Zendy; Yoshio Tanaka | Zendy; Koki Shigenobu | Zendy; Katsuo Koike | Zendy; Nobuo Suzuki | Zendy; Atsuhiko Hattori | Zendy

Open Access

The Ideal Synthetic Method Aimed at the Leads for an a2-Blocker, an Inhibitor of Blood Platelet Aggregation, and an Anti-osteoporosis Agent

Author(s) -

Masanori Somei,

Takako Iwaki,

Fumio Yamada,

Yoshio Tanaka,

Koki Shigenobu,

Katsuo Koike,

Nobuo Suzuki,

Atsuhiko Hattori

Publication year - 2006

Publication title -

heterocycles

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.242

H-Index - 64

eISSN - 1881-0942

pISSN - 0385-5414

DOI - 10.3987/com-06-10771

Subject(s) - chemistry , ideal (ethics) , originality , reagent , combinatorial chemistry , stereochemistry , organic chemistry , law , creativity , political science

According to the definition of the ideal synthetic method, an example aimed at the leads for an α 2 -blocker, an inhibitor of platelet aggregation, and an anti-osteoporosis agent is established starting from tryptamine. The originality rate, the intellectual property, and the application potential factors of the method are 71, 54, and 100, respectively. The method employs only conventional reagents and reaction conditions without using any protecting groups.

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