Open AccessCondensation of 4-Hydroxy-2-thiazolines with 1,2-Phenylenediamine as a Novel Effective Route to Thiazolo[3,4-a]quinoxalines
Author(s) -
Sadao Tsuboi,
В. А. Мамедов,
И. З. Нурхаметова,
А.Т. Губайдуллин,
I.А. Litvinov
Publication year - 2004
Publication title -
heterocycles
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.242
H-Index - 64
eISSN - 1881-0942
pISSN - 0385-5414
DOI - 10.3987/com-04-10084
Subject(s) - chemistry , condensation , combinatorial chemistry , organic chemistry , stereochemistry , thermodynamics , physics
Thiazolo[3,4-a]quinoxalin-4-ones were prepared in two steps starting from methyl phenylchloropyruvate using a new strategy for the construction of the ring system. A key step in this new method involves the reaction of 4-hydroxytetrahydrothiazoles with 1,2-phenylendiamines.
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