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A Combination of Single-Nucleotide Polymorphisms Is Associated with Interindividual Variability in Cholecalciferol Bioavailability in Healthy Men
Author(s) -
Charles Desmarchelier,
Patrick Borel,
Aurélie Goncalves,
Rachel E. Kopec,
Marion Nowicki,
Sophie Morange,
Nathalie Lesavre,
Henri Portugal,
Emmanuelle Reboul
Publication year - 2016
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.3945/jn.116.237115
Subject(s) - cholecalciferol , postprandial , medicine , single nucleotide polymorphism , endocrinology , chylomicron , vitamin d and neurology , bioavailability , biology , chemistry , cholesterol , genetics , lipoprotein , genotype , pharmacology , gene , very low density lipoprotein , insulin
Most people require dietary vitamin D to achieve the recommended concentration of 25-hydroxyvitamin D [25(OH)D] in the blood. However, the response to vitamin D supplementation is highly variable among individuals.

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