Protein Synthesis in Mucin-Producing Tissues Is Conserved When Dietary Threonine Is Limiting in Piglets | Zendy

Lalani L. Munasinghe | Zendy; Jason L. Robinson | Zendy; Scott Harding | Zendy; Janet A. Brunton | Zendy; Robert F. Bertolo | Zendy

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Protein Synthesis in Mucin-Producing Tissues Is Conserved When Dietary Threonine Is Limiting in Piglets

Author(s) -

Lalani L. Munasinghe,

Jason L. Robinson,

Scott Harding,

Janet A. Brunton,

Robert F. Bertolo

Publication year - 2017

Publication title -

journal of nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.463

H-Index - 265

eISSN - 1541-6100

pISSN - 0022-3166

DOI - 10.3945/jn.116.236786

Subject(s) - threonine , jejunum , mucin , ileum , phenylalanine , biochemistry , biology , chemistry , amino acid , serine , medicine , phosphorylation

The neonatal gastrointestinal tract extracts the majority of dietary threonine on the first pass to maintain synthesis of threonine-rich mucins in mucus. As dietary threonine becomes limiting, this extraction must limit protein synthesis in extraintestinal tissues at the expense of maintaining protein synthesis in mucin-producing tissues.

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