Common Polymorphisms That Affect Folate Transport or Metabolism Modify the Effect of the MTHFR 677C > T Polymorphism on Folate Status
Author(s) -
Olalla Bueno,
Anne M. Molloy,
Joan FernándezBallart,
Carlos J. García-Minguillán,
Santiago Ceruelo,
Lídia Ríos,
Per Magne Ueland,
Klaus Meyer,
Michelle M. Murphy
Publication year - 2015
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.3945/jn.115.223685
Subject(s) - mtrr , methylenetetrahydrofolate reductase , homocysteine , reductase , medicine , methionine synthase , methionine , chemistry , endocrinology , genetics , genotype , biology , biochemistry , enzyme , amino acid , gene
Although combinations of biologically relevant polymorphic variants affect folate status, most studies have focused on the effects of individual polymorphisms; however, these effects may be altered by interactions between polymorphisms.
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