Energy and Protein Supplementation Does Not Affect Protein and Amino Acid Kinetics or Pregnancy Outcomes in Underweight Indian Women | Zendy

Pratibha Dwarkanath | Zendy; Jean W. Hsu | Zendy; Grace J. Tang | Zendy; Pauline Anand | Zendy; Tinku Thomas | Zendy; Annamma Thomas | Zendy; C. N. Sheela | Zendy; Anura V. Kurpad | Zendy; Farook Jahoor | Zendy

Open Access

Energy and Protein Supplementation Does Not Affect Protein and Amino Acid Kinetics or Pregnancy Outcomes in Underweight Indian Women

Author(s) -

Pratibha Dwarkanath,

Jean W. Hsu,

Grace J. Tang,

Pauline Anand,

Tinku Thomas,

Annamma Thomas,

C. N. Sheela,

Anura V. Kurpad,

Farook Jahoor

Publication year - 2016

Publication title -

journal of nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.463

H-Index - 265

eISSN - 1541-6100

pISSN - 0022-3166

DOI - 10.3945/jn.115.218776

Subject(s) - pregnancy , underweight , medicine , endocrinology , gestation , methionine , body mass index , transmethylation , fetus , biology , chemistry , amino acid , overweight , biochemistry , genetics

In India, the prevalence of low birth weight is high in women with a low body mass index (BMI), suggesting that underweight women are not capable of providing adequate energy and protein for fetal growth. Furthermore, as pregnancy progresses, there is increased need to provide methyl groups for methylation reactions associated with the synthesis of new proteins and, unlike normal-BMI American women, low-BMI Indian women are unable to increase methionine transmethylation and remethylation rates as pregnancy progresses from trimester 1 to 3. This also negatively influences birth weight.

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