Open AccessDietary Fat Intake Modifies the Effect of a Common Variant in the LIPC Gene on Changes in Serum Lipid Concentrations during a Long-Term Weight-Loss Intervention Trial
Author(s) -
Min Xu,
San San Ng,
George A. Bray,
Donna H. Ryan,
Frank M. Sacks,
Guang Ning,
Lu Qi
Publication year - 2015
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.3945/jn.115.212514
Subject(s) - medicine , endocrinology , cholesterol , overweight , hepatic lipase , chemistry , obesity , weight loss , biology , lipoprotein
Hepatic lipase (HL) plays a pivotal role in the metabolism of HDL and LDL. Recent genome-wide association studies have identified common variants in the HL gene (LIPC) associated with HDL cholesterol.
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