Maternal Choline Status, but Not Fetal Genotype, Influences Cord Plasma Choline Metabolite Concentrations | Zendy

Carly Visentin | Zendy; Shan Masih | Zendy; Lesley Plumptre | Zendy; Olga Malysheva | Zendy; Daiva E. Nielsen | Zendy; KyoungJin Sohn | Zendy; Anna Ly | Zendy; Andrea Lausman | Zendy; Howard Berger | Zendy; Ruth Croxford | Zendy; Ahmed ElSohemy | Zendy; Marie A. Caudill | Zendy; Deborah L. O’Connor | Zendy; YoungIn Kim | Zendy

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Maternal Choline Status, but Not Fetal Genotype, Influences Cord Plasma Choline Metabolite Concentrations

Author(s) -

Carly Visentin,

Shan Masih,

Lesley Plumptre,

Olga Malysheva,

Daiva E. Nielsen,

KyoungJin Sohn,

Anna Ly,

Andrea Lausman,

Howard Berger,

Ruth Croxford,

Ahmed ElSohemy,

Marie A. Caudill,

Deborah L. O’Connor,

YoungIn Kim

Publication year - 2015

Publication title -

journal of nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.463

H-Index - 265

eISSN - 1541-6100

pISSN - 0022-3166

DOI - 10.3945/jn.115.211136

Subject(s) - choline , metabolite , genotype , fetus , chemistry , endocrinology , medicine , biology , pregnancy , biochemistry , genetics , gene

Choline deficiency during pregnancy can lead to adverse birth outcomes, including impaired neurodevelopment and birth defects. Genetic variants of choline and one-carbon metabolism may also influence birth outcomes by altering plasma choline concentrations. The effects of maternal ad libitum choline intake during pregnancy and fetal genetic variants on maternal and cord concentrations of choline and its metabolites are unknown.

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