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Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites
Author(s) -
Pei Wang,
Huadong Chen,
Yingdong Zhu,
Jennifer E. McBride,
Junsheng Fu,
Shengmin Sang
Publication year - 2014
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.3945/jn.114.206508
Subject(s) - urine , metabolism , caffeic acid , ferulic acid , chemistry , feces , bioavailability , metabolite , metabolome , metabolomics , apoptosis , metabolic pathway , high performance liquid chromatography , biochemistry , pharmacology , chromatography , biology , antioxidant , microbiology and biotechnology
Avenanthramides (AVAs), which are found exclusively in oats, may play an important role in anti-inflammation and antiatherogenesis. Although the bioavailability of AVAs has been investigated previously, little is known about their metabolism.

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