Eicosapentaenoic Acid Reduces Adipocyte Hypertrophy and Inflammation in Diet-Induced Obese Mice in an Adiposity-Independent Manner,
Author(s) -
Monique LeMieux,
Nishan S. Kalupahana,
Shane Scoggin,
Naïma MoustaïdMoussa
Publication year - 2015
Publication title -
journal of nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.463
H-Index - 265
eISSN - 1541-6100
pISSN - 0022-3166
DOI - 10.3945/jn.114.202952
Subject(s) - medicine , endocrinology , adipose tissue , adipocyte , eicosapentaenoic acid , white adipose tissue , inflammation , obesity , insulin resistance , adiponectin , biology , polyunsaturated fatty acid , fatty acid , biochemistry
Obesity is associated with an overexpansion of adipose tissue, along with increases in blood pressure, glycemia, inflammation, and thrombosis. Research to develop nutritional interventions to prevent or treat obesity and its associated diseases is greatly needed. Previously, we demonstrated the ability of eicosapentaenoic acid (EPA) to prevent high-fat (HF) diet-induced obesity, insulin resistance, and inflammation in mice.
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