The Relative Bioavailability of the Calcium Salt of β-Hydroxy-β-Methylbutyrate Is Greater Than That of the Free Fatty Acid Form in Rats | Zendy

Sathyavageeswaran Shreeram | Zendy; Paul W. Johns | Zendy; Swaminathan Subramaniam | Zendy; Subbarayan Ramesh | Zendy; Vadakkanchery V. Vaidyanathan | Zendy; Jithesh K. Puthan | Zendy; Shibajee Mandal | Zendy; Vijay Kumar Mamidi | Zendy; Richard W. Gelling | Zendy

Open Access

The Relative Bioavailability of the Calcium Salt of β-Hydroxy-β-Methylbutyrate Is Greater Than That of the Free Fatty Acid Form in Rats

Author(s) -

Sathyavageeswaran Shreeram,

Paul W. Johns,

Swaminathan Subramaniam,

Subbarayan Ramesh,

Vadakkanchery V. Vaidyanathan,

Jithesh K. Puthan,

Shibajee Mandal,

Vijay Kumar Mamidi,

Richard W. Gelling

Publication year - 2014

Publication title -

journal of nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.463

H-Index - 265

eISSN - 1541-6100

pISSN - 0022-3166

DOI - 10.3945/jn.114.196527

Subject(s) - bioavailability , cmax , pharmacokinetics , chemistry , oral administration , calcium , pharmacology , chromatography , endocrinology , fatty acid , medicine , biochemistry , organic chemistry

β-Hydroxy-β-methylbutyrate (HMB) supplementation has been demonstrated to enhance muscle protein synthesis and attenuate loss of muscle mass by multiple pathways. The beneficial effects of HMB have been studied by using either the calcium salt, monohydrate, of HMB (CaHMB) or the free acid form (FAHMB).

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