Pregnancy and Lactation Alter Biomarkers of Biotin Metabolism in Women Consuming a Controlled Diet | Zendy

Cydne A. Perry | Zendy; Allyson A. West | Zendy; Antoinette Gayle | Zendy; Lauren K. Lucas | Zendy; Jian Yan | Zendy; Xinyin Jiang | Zendy; Olga Malysheva | Zendy; Marie A. Caudill | Zendy

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Pregnancy and Lactation Alter Biomarkers of Biotin Metabolism in Women Consuming a Controlled Diet

Author(s) -

Cydne A. Perry,

Allyson A. West,

Antoinette Gayle,

Lauren K. Lucas,

Jian Yan,

Xinyin Jiang,

Olga Malysheva,

Marie A. Caudill

Publication year - 2014

Publication title -

journal of nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.463

H-Index - 265

eISSN - 1541-6100

pISSN - 0022-3166

DOI - 10.3945/jn.114.194472

Subject(s) - biotin , carnitine , endocrinology , pyruvate carboxylase , medicine , lactation , pregnancy , metabolite , biotin deficiency , urine , metabolism , physiology , biology , vitamin , biochemistry , enzyme , genetics

Biotin functions as a cofactor for several carboxylase enzymes with key roles in metabolism. At present, the dietary requirement for biotin is unknown and intake recommendations are provided as Adequate Intakes (AIs). The biotin AI for adults and pregnant women is 30 μg/d, whereas 35 μg/d is recommended for lactating women. However, pregnant and lactating women may require more biotin to meet the demands of these reproductive states.

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