Gut Microbiota in Obesity and Undernutrition | Zendy

Nicolien C. de Clercq | Zendy; Albert K. Groen | Zendy; Johannes A. Romijn | Zendy; Max Nieuwdorp | Zendy

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Gut Microbiota in Obesity and Undernutrition

Author(s) -

Nicolien C. de Clercq,

Albert K. Groen,

Johannes A. Romijn,

Max Nieuwdorp

Publication year - 2016

Publication title -

advances in nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.362

H-Index - 90

eISSN - 2156-5376

pISSN - 2161-8313

DOI - 10.3945/an.116.012914

Subject(s) - malnutrition , obesity , gut flora , energy homeostasis , medicine , energy expenditure , intensive care medicine , biology , bioinformatics , immunology

Malnutrition is the result of an inadequate balance between energy intake and energy expenditure that ultimately leads to either obesity or undernutrition. Several factors are associated with the onset and preservation of malnutrition. One of these factors is the gut microbiota, which has been recognized as an important pathophysiologic factor in the development and sustainment of malnutrition. However, to our knowledge, the extent to which the microbiota influences malnutrition has yet to be elucidated. In this review, we summarize the mechanisms via which the gut microbiota may influence energy homeostasis in relation to malnutrition. In addition, we discuss potential therapeutic modalities to ameliorate obesity or undernutrition.

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