Modulation of the Gut Microbiota by Nutrients with Prebiotic and Probiotic Properties | Zendy

Céline Druart | Zendy; Maud Alligier | Zendy; Nuria Salazar | Zendy; Audrey M. Neyrinck | Zendy; Nathalie M. Delzenne | Zendy

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Modulation of the Gut Microbiota by Nutrients with Prebiotic and Probiotic Properties

Author(s) -

Céline Druart,

Maud Alligier,

Nuria Salazar,

Audrey M. Neyrinck,

Nathalie M. Delzenne

Publication year - 2014

Publication title -

advances in nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.362

H-Index - 90

eISSN - 2156-5376

pISSN - 2161-8313

DOI - 10.3945/an.114.005835

Subject(s) - prebiotic , gut flora , probiotic , obesity , biology , adipose tissue , fatty liver , disease , medicine , physiology , endocrinology , immunology , food science , bacteria , genetics

Experimental data in animals, but also observational studies in humans, suggest that the composition of the gut microbiota differs in obese vs. lean individuals, in patients with vs. without diabetes, or in patients presenting other diseases associated with obesity or nutritional disbalance, such as non-alcoholic fatty liver disease (NAFLD) or cardiovascular diseases. In this review, we describe how changes in the composition and/or activity of the gut microbiota by administration of nutrients with probiotic or prebiotic properties can modulate host gene expression and metabolism and thereby positively influence host adipose tissue development and related metabolic disorders.

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