Open AccessIncreased breast cancer risk at high plasma folate concentrations among women with the MT HFR 677T allele
Author(s) -
Ulrika Ericson,
Malin Ivarsson,
Emily Sonestedt,
Bo Gullberg,
Joyce Carlson,
Håkan Olsson,
Elisabet Wirfält
Publication year - 2009
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.2009.28064
Subject(s) - methylenetetrahydrofolate reductase , breast cancer , genotype , single nucleotide polymorphism , nested case control study , odds ratio , medicine , allele , case control study , endocrinology , oncology , cancer , gastroenterology , genetics , biology , gene
Folate is involved in DNA synthesis and methylation and may thereby influence carcinogenesis.
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