Physical activity attenuates the body mass index–increasing influence of genetic variation in the FTO gene
Author(s) -
Karani S. Vimaleswaran,
Shengxu Li,
Jing Hua Zhao,
Jian’an Luan,
Sheila Bingham,
KayTee Khaw,
Ulf Ekelund,
Nicholas J. Wareham,
Ruth J. F. Loos
Publication year - 2009
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.2009.27652
Subject(s) - body mass index , obesity , allele , waist , medicine , population , minor allele frequency , genotype , cohort , allele frequency , endocrinology , genetics , biology , gene , environmental health
Intronic variation in the FTO (fat mass and obesity-associated) gene has been unequivocally associated with increased body mass index (BMI; in kg/m(2)) and the risk of obesity in populations of different ethnicity.
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