Open AccessSevere obesity is associated with novel single nucleotide polymorphisms of theESR1 and PPARγ locus in Han Chinese
Author(s) -
Hsin-Hung Chen,
WenJeng Lee,
Cathy S.J. Fann,
Claude Bouchard,
WenHarn Pan
Publication year - 2009
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.2009.25914
Subject(s) - single nucleotide polymorphism , obesity , odds ratio , body mass index , medicine , case control study , genetics , candidate gene , bioinformatics , biology , gene , genotype
A large number of potential obesity loci have been reported. At least 18 genes have been replicated in a minimum of 5 studies on obesity-related phenotypes. Fourteen additional genes have been associated with obesity in Asians.
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