Needle and surgical biopsy techniques differentially affect adipose tissue gene expression profiles
Author(s) -
David M. Mutch,
Joan Tordjman,
Véronique Pelloux,
Blaise Hanczar,
Cornéliu Henegar,
Christine Poitou,
Nicolas Veyrie,
JeanDaniel Zucker,
Karine Clément
Publication year - 2008
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.2008.26802
Subject(s) - adipose tissue , biopsy , pathology , immunohistochemistry , gene expression , medicine , microarray , biology , bioinformatics , gene , genetics
Adipose tissue gene expression analysis in humans now provides a tremendous means to discover the physiopathologic gene targets critical for our understanding and treatment of obesity. Clinical studies are emerging in which adipose gene expression has been examined in hundreds of subjects, and it will be fundamentally important that these studies can be compared so that a common consensus can be reached and new therapeutic targets for obesity proposed.
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