ATP-binding cassette transporter A1 is significantly involved in the intestinal absorption of α- and γ-tocopherol but not in that of retinyl palmitate in mice
Author(s) -
Emmanuelle Reboul,
Doriane Trompier,
Myriam Moussa,
Alexis Klein,
JeanFrançois Landrier,
Giovanna Chimini,
Patrick Borel
Publication year - 2008
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.2008.26559
Subject(s) - abca1 , retinyl palmitate , chylomicron , endocrinology , medicine , chemistry , vitamin , tocopherol , in vivo , transporter , biology , biochemistry , retinol , lipoprotein , cholesterol , vitamin e , very low density lipoprotein , antioxidant , gene , microbiology and biotechnology
It has long been assumed that newly absorbed vitamin A and E enter the body only via enterocyte-produced chylomicrons. However, recent results in cell cultures have shown that a fraction of alpha-tocopherol is secreted with intestinal HDL.
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