High-fructose corn syrup, energy intake, and appetite regulation | Zendy

Kathleen J. Melanson | Zendy; Theodore J. Angelopoulos | Zendy; Von Nguyen | Zendy; Linda Zukley | Zendy; Joshua Lowndes | Zendy; James M. Rippe | Zendy

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High-fructose corn syrup, energy intake, and appetite regulation

Author(s) -

Kathleen J. Melanson,

Theodore J. Angelopoulos,

Von Nguyen,

Linda Zukley,

Joshua Lowndes,

James M. Rippe

Publication year - 2008

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.3945/ajcn.2008.25825e

Subject(s) - high fructose corn syrup , appetite , ghrelin , corn syrup , leptin , fructose , sucrose , food science , endocrinology , weight gain , glucose syrup , energy balance , medicine , obesity , chemistry , body weight , sugar , hormone , biology , ecology

High-fructose corn syrup (HFCS) has been implicated in excess weight gain through mechanisms seen in some acute feeding studies and by virtue of its abundance in the food supply during years of increasing obesity. Compared with pure glucose, fructose is thought to be associated with insufficient secretion of insulin and leptin and suppression of ghrelin. However, when HFCS is compared with sucrose, the more commonly consumed sweetener, such differences are not apparent, and appetite and energy intake do not differ in the short-term. Longer-term studies on connections between HFCS, potential mechanisms, and body weight have not been conducted. The main objective of this review was to examine collective data on associations between consumption of HFCS and energy balance, with particular focus on energy intake and its regulation.

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