Open AccessGlycomacropeptide for nutritional management of phenylketonuria: a randomized, controlled, crossover trial
Author(s) -
Denise M. Ney,
Bridget M. Stroup,
Murray K. Clayton,
Sangita G. Murali,
Gregory M. Rice,
Frances Rohr,
Harvey L. Levy
Publication year - 2016
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.116.135293
Subject(s) - crossover study , phenylalanine , medicine , dietary management , washout , randomized controlled trial , endocrinology , amino acid , chemistry , biochemistry , pathology , placebo , alternative medicine
To prevent cognitive impairment, phenylketonuria requires lifelong management of blood phenylalanine (Phe) concentration with a low-Phe diet. The diet restricts intake of Phe from natural proteins in combination with traditional amino acid medical foods (AA-MFs) or glycomacropeptide medical foods (GMP-MFs) that contain primarily intact protein and a small amount of Phe.
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