The association of serum choline with linear growth failure in young children from rural Malawi | Zendy

Richard D. Semba | Zendy; Pingbo Zhang | Zendy; Marta GonzálezFreire | Zendy; Ruin Moaddel | Zendy; Indi Trehan | Zendy; Kenneth Maleta | Zendy; M. Isabel Ordiz | Zendy; Luigi Ferrucci | Zendy; Mark Manary | Zendy

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The association of serum choline with linear growth failure in young children from rural Malawi

Author(s) -

Richard D. Semba,

Pingbo Zhang,

Marta GonzálezFreire,

Ruin Moaddel,

Indi Trehan,

Kenneth Maleta,

M. Isabel Ordiz,

Luigi Ferrucci,

Mark Manary

Publication year - 2016

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.3945/ajcn.115.129684

Subject(s) - choline , betaine , chemistry , medicine , endocrinology , percentile , biochemistry , statistics , mathematics

Choline is an essential nutrient for cell structure, cell signaling, neurotransmission, lipid transport, and bone formation. Choline can be irreversibly converted to betaine, a major source of methyl groups. Trimethylene N-oxide (TMAO), a proatherogenic molecule, is produced from the metabolism of dietary choline by the gut microbiome. The relation between serum choline and its closely related metabolites with linear growth in children is unknown.

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