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Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis,
Author(s) -
Katherine Meckel,
Yan Chun Li,
John Lim,
Masha Kocherginsky,
Christopher R. Weber,
Anas Almoghrabi,
Xindi Chen,
Austin Kaboff,
Farhana Sadiq,
Stephen B. Hanauer,
Russell D. Cohen,
John H. Kwon,
David T. Rubin,
Ira M. Hanan,
Atsushi Sakuraba,
Eugene F. Yen,
Marc Bissonnette,
Joel Pekow
Publication year - 2016
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.115.123786
Subject(s) - ulcerative colitis , inflammation , mucosal inflammation , gastroenterology , medicine , colitis , vitamin d and neurology , immunology , disease
Vitamin D exerts anti-inflammatory actions both in vitro and in murine models of colitis. In previous studies, we demonstrated that vitamin D protects against the development of colitis by maintaining the integrity of the intestinal mucosal barrier.

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