Open AccessCombined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial
Author(s) -
Jasper Most,
Silvie Timmers,
Ines Warnke,
Johan W. E. Jocken,
Mark V. Boekschoten,
Philip de Groot,
Igor Bendik,
Patrick Schrauwen,
Gijs H. Goossens,
Ellen E. Blaak
Publication year - 2016
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.115.122937
Subject(s) - epigallocatechin gallate , insulin sensitivity , randomized controlled trial , resveratrol , chemistry , endocrinology , medicine , food science , insulin , biochemistry , insulin resistance , polyphenol , antioxidant
The obese insulin-resistant state is characterized by impairments in lipid metabolism. We previously showed that 3-d supplementation of combined epigallocatechin-3-gallate and resveratrol (EGCG+RES) increased energy expenditure and improved the capacity to switch from fat toward carbohydrate oxidation with a high-fat mixed meal (HFMM) test in men.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom