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Postdiagnostic intake of one-carbon nutrients and alcohol in relation to colorectal cancer survival
Author(s) -
Paul Lochhead,
Reiko Nishihara,
Zhi Rong Qian,
Kosuke Mima,
Yin Cao,
Yasutaka Sukawa,
Sun A. Kim,
Kentaro Inamura,
Xuehong Zhang,
Kana Wu,
Edward L. Giovannucci,
Jeffrey A. Meyerhardt,
Andrew T. Chan,
Charles S. Fuchs,
Shuji Ogino
Publication year - 2015
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.115.115162
Subject(s) - nutrient , colorectal cancer , alcohol intake , alcohol , cancer , relation (database) , medicine , environmental health , oncology , biology , biochemistry , computer science , ecology , database
Observational data have suggested that intakes of nutrients involved in one-carbon metabolism are inversely associated with risk of colorectal carcinoma and adenomas. In contrast, results from some preclinical studies and cardiovascular and chemoprevention trials have raised concerns that high folate intake may promote carcinogenesis by facilitating the progression of established neoplasia.

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