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High concentrations of folate and unmetabolized folic acid in a cohort of pregnant Canadian women and umbilical cord blood
Author(s) -
Lesley Plumptre,
Shan Masih,
Anna Ly,
Susanne Aufreiter,
KyoungJin Sohn,
Ruth Croxford,
Andrea Lausman,
Howard Berger,
Deborah L. O’Connor,
YoungIn Kim
Publication year - 2015
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.115.110783
Subject(s) - methylenetetrahydrofolate reductase , cord blood , pregnancy , medicine , umbilical cord , physiology , fetus , dihydrofolate reductase , obstetrics , prospective cohort study , andrology , methotrexate , immunology , biochemistry , biology , genotype , genetics , gene
Mandatory fortification, prevalent supplement use, and public health guidelines recommending periconceptional supplementation have increased folic acid intakes in North American pregnant women. However, the effects of increased folic acid intakes during pregnancy on maternal and cord blood folate concentrations have not been well established.

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