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Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food
Author(s) -
Anthony P. Goldstone,
Christina Prechtl,
Samantha Scholtz,
Alexander D. Miras,
Navpreet Chhina,
Giuliana Durighel,
Seyedeh S Deliran,
Christian F. Beckmann,
Mohammad A. Ghatei,
Damien Ashby,
Adam Waldman,
Bruce D. Gaylinn,
Michael O. Thorner,
Gary Frost,
Stephen R. Bloom,
Jimmy D. Bell
Publication year - 2014
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.113.075291
Subject(s) - orbitofrontal cortex , ghrelin , hippocampal formation , neuroscience , prefrontal cortex , psychology , medicine , endocrinology , cognition , receptor
Ghrelin, which is a stomach-derived hormone, increases with fasting and energy restriction and may influence eating behaviors through brain hedonic reward-cognitive systems. Therefore, changes in plasma ghrelin might mediate counter-regulatory responses to a negative energy balance through changes in food hedonics.

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