Vitamin A isotope dilution predicts liver stores in line with long-term vitamin A intake above the current Recommended Dietary Allowance for young adult women
Author(s) -
Ashley R Valentine,
Christopher R. Davis,
Sherry A. Tanumihardjo
Publication year - 2013
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.113.063867
Subject(s) - dietary reference intake , isotope dilution , vitamin , retinol , reference daily intake , endocrinology , medicine , population , zoology , physiology , chemistry , biology , nutrient , environmental health , chromatography , mass spectrometry , organic chemistry
The Estimated Average Requirement (EAR) and Recommended Dietary Allowance (RDA) for vitamin A are 1.7 and 2.4 μmol/d (500 and 700 μg retinol activity equivalents/d), respectively, for nonpregnant, nonlactating women aged >19 y. This intake is presumed to maintain a minimally acceptable liver concentration of 0.07 μmol (20 μg) retinol/g; however, liver reserves have not been evaluated with respect to vitamin A intake in women of any age group defined in the Dietary Reference Intakes.
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