Open AccessMetabolomic profile of response to supplementation with β-carotene in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
Author(s) -
Alison M. Mondul,
Joshua N. Sampson,
Steven C. Moore,
Stephanie J. Weinstein,
Anne M. Evans,
Edward D. Karoly,
Jarmo Virtamo,
Demetrius Albanes
Publication year - 2013
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.113.062778
Subject(s) - carotene , cancer prevention , medicine , beta carotene , placebo , metabolomics , metabolite , randomized controlled trial , physiology , cancer , vitamin , pharmacology , bioinformatics , biology , food science , pathology , alternative medicine
Two chemoprevention trials found that supplementation with β-carotene increased the risk of lung cancer and overall mortality. The biologic basis of these findings remains poorly understood.
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