Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers | Zendy

Fabrice H.F. Pierre | Zendy; Océane Martin | Zendy; Raphaëlle L. Santarelli | Zendy; Sylviane Taché | Zendy; Nathalie Naud | Zendy; Françoise Guéraud | Zendy; Marc Audebert | Zendy; Jacques Dupuy | Zendy; Nathalie Meunier | Zendy; Didier Attaix | Zendy; JeanLuc Vendeuvre | Zendy; Sidney S. Mirvish | Zendy; Gunter G. C. Kuhnle | Zendy; Noël Cano | Zendy; Denis E. Corpet | Zendy

Open Access

Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers

Author(s) -

Fabrice H.F. Pierre,

Océane Martin,

Raphaëlle L. Santarelli,

Sylviane Taché,

Nathalie Naud,

Françoise Guéraud,

Marc Audebert,

Jacques Dupuy,

Nathalie Meunier,

Didier Attaix,

JeanLuc Vendeuvre,

Sidney S. Mirvish,

Gunter G. C. Kuhnle,

Noël Cano,

Denis E. Corpet

Publication year - 2013

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.3945/ajcn.113.061069

Subject(s) - calcium , feces , colorectal cancer , food science , chemistry , vitamin e , carcinogen , red meat , tocopherol , medicine , physiology , endocrinology , biochemistry , antioxidant , cancer , biology , microbiology and biotechnology

Processed meat intake has been associated with increased colorectal cancer risk. We have shown that cured meat promotes carcinogen-induced preneoplastic lesions and increases specific biomarkers in the colon of rats.

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