Open AccessAPOA5 genotype modulates 2-y changes in lipid profile in response to weight-loss diet intervention: the Pounds Lost Trial
Author(s) -
Xiaomin Zhang,
Qibin Qi,
George A. Bray,
Frank B. Hu,
Frank M. Sacks,
Lu Qi
Publication year - 2012
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.112.040907
Subject(s) - weight loss , genotype , intervention (counseling) , medicine , gerontology , biology , zoology , endocrinology , obesity , genetics , gene , psychiatry
The apolipoprotein A5 gene (APOA5) is a major gene that regulates lipid metabolism and is modulated by dietary factors. A novel variant rs964184 in APOA5 was identified to be associated with lipids in genome-wide association studies.
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