Determinants of urinary methylmalonic acid concentration in an elderly population in the United Kingdom | Zendy

Janet Flatley | Zendy; Clare M. Garner | Zendy; Maha Al Turki | Zendy; N. J. Manning | Zendy; S. E. Olpin | Zendy; Margo E. Barker | Zendy; Hilary J. Powers | Zendy

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Determinants of urinary methylmalonic acid concentration in an elderly population in the United Kingdom

Author(s) -

Janet Flatley,

Clare M. Garner,

Maha Al Turki,

N. J. Manning,

S. E. Olpin,

Margo E. Barker,

Hilary J. Powers

Publication year - 2012

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.3945/ajcn.111.024133

Subject(s) - methylmalonic acid , urinary system , kingdom , medicine , urine , biology , vitamin b12 , botany

An age-related deterioration of vitamin B-12 status has been well documented. The early detection of deficiency may prevent the development of serious clinical symptoms, but plasma vitamin B-12 concentration is known to be an imperfect measure of vitamin B-12 status. Urinary methylmalonic acid (MMA) may be a more informative biomarker of vitamin B-12 status; however, biochemical, dietary, and other lifestyle determinants are not known.

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