Increases in central fat mass and decreases in peripheral fat mass are associated with accelerated arterial stiffening in healthy adults: the Amsterdam Growth and Health Longitudinal Study
Author(s) -
Fleur Schouten,
Jos W. R. Twisk,
Michiel R. de Boer,
Coen D.A. Stehouwer,
Erik H. Serné,
Yvo M. Smulders,
Isabel Ferreira
Publication year - 2011
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.3945/ajcn.111.013532
Subject(s) - arterial stiffness , pulse wave velocity , medicine , peripheral , trunk , lean body mass , population , endocrinology , body mass index , cardiology , blood pressure , biology , body weight , ecology , environmental health
Central fatness is associated with higher arterial stiffness, a mechanism that may explain adiposity-related increases in cardiovascular disease risk. In contrast, peripheral fat and lean masses may counteract such adverse effects, but evidence of this contention, as derived from longitudinal studies at the general population level, is lacking.
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