EFFECT OF BLEEDING TO NERVE REGENERATION AND EPINEURAL SCAR FORMATION IN RAT SCIATIC NERVES (EXPERIMENTAL STUDY) | Zendy

Erkan Servet | Zendy; Halil Bekler | Zendy; Volkan Kılınçoğlu | Zendy; Turhan Özler | Zendy; Afşar T. Özkut | Zendy

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EFFECT OF BLEEDING TO NERVE REGENERATION AND EPINEURAL SCAR FORMATION IN RAT SCIATIC NERVES (EXPERIMENTAL STUDY)

Author(s) -

Erkan Servet,

Halil Bekler,

Volkan Kılınçoğlu,

Turhan Özler,

Afşar T. Özkut

Publication year - 2015

Publication title -

acta orthopaedica et traumatologica turcica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.586

H-Index - 28

eISSN - 2589-1294

pISSN - 1017-995X

DOI - 10.3944/aott.2015.15.0090

Subject(s) - medicine , sciatic nerve , saline , regeneration (biology) , surgery , anesthesia , wound healing , anatomy , biology , microbiology and biotechnology

Epineural scar formation is one of the most significant negative factors affecting surgical repair after peripheral nerve injury. The scar tissue mechanically hinders axonal regeneration and causes adhesions between nerves and surrounding tissues. A hemostatic agent Ankaferd Blood Stopper (ABS; İmmun Gıda İlaç Kozmetik San. ve Tic. Ltd. Şti., Istanbul, Turkey) has not been previously used. Decreasing the postoperative bleeding and adhesions between nerve and surrounding tissues will prevent the formation of scar tissue, as well as corresponding compressive neuropathy and/or deceleration of axonal regeneration. The purpose of this experimental study was to investigate the effects of bleeding on nerve healing and scar tissue after repair of peripheral nerve injuries.

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