Coarse-grained Simulations of Biological Motors

Fig. 1. A cartoon illustrating a kinesin stepping on a microtubule track. Kinesin has two motor domains (two brown objects) to alternately bind microtubule binding sites whose affinity changes with the chemical state of nucleotide (ATP, ADP, or nucleotide free state) in the catalytic site. Tail domain extended from the motor domains is linked to a tail binding domain with which kinesins can carry cellular organelles such as vesicle, mRNA, and mitochondria along microtubules.