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In this paper, we consider a system of reaction-diffusion equations in a domain consisting of two bulk regions separated by a thin layer with thickness of order $e$ and a periodic heterogeneous structure. The equations inside the layer depend on $e$ and the diffusivity inside the layer on an additional parameter $γ ∈ [-1, 1]$. On the bulk-layer interface, we assume a nonlinear Neumann-transmission condition depending on the solutions on both sides of the interface. For $\epsilon \to0 $, when the thin layer reduces to an interface $Σ$ between two bulk domains, we rigorously derive macroscopic models with effective conditions across the interface $Σ$. The crucial part is to pass to the limit in the nonlinear terms, especially for the traces on the interface between the different compartments. For this purpose, we use the method of two-scale convergence for thin heterogeneous layers, and a Kolmogorov-type compactness result for Banach valued functions, applied to the unfolded sequence in the thin layer.

Effective interface conditions for processes through thin heterogeneous layers with nonlinear transmission at the microscopic bulk-layer interface