Evaluation of Oxidative Stress Response Related Genetic Variants, Pro-oxidants, Antioxidants and Prostate Cancer | Zendy

Nicole Lavender | Zendy; David W. Hein | Zendy; Guy Brock | Zendy; La Creis R. Kidd | Zendy

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Evaluation of Oxidative Stress Response Related Genetic Variants, Pro-oxidants, Antioxidants and Prostate Cancer

Author(s) -

Nicole Lavender,

David W. Hein,

Guy Brock,

La Creis R. Kidd

Publication year - 2015

Publication title -

aims medical science

Language(s) - English

Resource type - Journals

eISSN - 2375-1576

pISSN - 2375-155X

DOI - 10.3934/medsci.2015.4.271

Subject(s) - prostate cancer , oxidative stress , allele , genetics , multifactor dimensionality reduction , biology , genotype , gene , cancer , single nucleotide polymorphism , endocrinology

Oxidative stress and detoxification mechanisms have been commonly studied in Prostate Cancer (PCa) due to their function in the detoxification of potentially damaging reactive oxygen species (ROS) and carcinogens. However, findings have been either inconsistent or inconclusive. These mixed findings may, in part, relate to failure to consider interactions among oxidative stress response related genetic variants along with pro- and antioxidant factors.

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