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Even though interleukin-1 receptor antagonist, IL-1Ra, is used in certain inflammatory diseases, its effect on ischemia-reperfusion injury is a current research topic. We aimed to investigate the protective effects of anakinra, an IL-1Ra, on the I/R induced intestinal injury.

The role of anakinra in the modulation of intestinal cell apoptosis and inflammatory response during ischemia/reperfusion