Lycopene sensitizes the cervical cancer cells to cisplatin via targeting nuclear factor- kappa B (NF-κB) pathway | Zendy

Oktay Halit Aktepe | Zendy; Taha Koray Şahin | Zendy; Gürkan Güner | Zendy; Zafer Arık | Zendy; Şuayib Yalçın | Zendy

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Lycopene sensitizes the cervical cancer cells to cisplatin via targeting nuclear factor- kappa B (NF-κB) pathway

Author(s) -

Oktay Halit Aktepe,

Taha Koray Şahin,

Gürkan Güner,

Zafer Arık,

Şuayib Yalçın

Publication year - 2020

Publication title -

turkish journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 27

eISSN - 1303-6165

pISSN - 1300-0144

DOI - 10.3906/sag-2005-413

Subject(s) - lycopene , hela , cisplatin , viability assay , medicine , cancer research , cancer cell , western blot , nf κb , cell , microbiology and biotechnology , pharmacology , cancer , immunology , biology , biochemistry , chemotherapy , antioxidant , inflammation , gene

Lycopene is associated with anticancer effects in various tumor types. However, the exact underlying mechanisms of action of lycopene in human cervical cancer remain to be determined. This study aimed to determine anticancer efficacy and mechanism of lycopene in human cervical carcinoma (HeLa) cells.

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