IFN-? stimulated dental follicle mesenchymal stem cells regulate activated lymphocyte response in rheumatoid arthritis patients in vitro
Author(s) -
Noushin Zibandeh,
Deniz Genç,
Nevsun İnanç,
Haner Di̇reskeneli̇,
Tunç Akkoç
Publication year - 2019
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1812-152
Subject(s) - medicine , il 2 receptor , mesenchymal stem cell , foxp3 , immunology , peripheral blood mononuclear cell , rheumatoid arthritis , stem cell , flow cytometry , lymphocyte , cytokine , immune system , in vitro , t cell , microbiology and biotechnology , pathology , biology , biochemistry
Multipotent mesenchymal stem cells (MSCs) have been investigated in autoimmune diseases such as rheumatoid arthritis (RA) due to their immunomodulatory and regenerative properties. In this study, their immunosuppressive effects on peripheral blood mononuclear cells (PBMC) of RA patients were studied.
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