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Identification of the cysteine-rich 61 (CYR61) gene variations in osteosarcoma patients
Author(s) -
Syed Rizwan Hussain,
Sabir Ali,
Ajai Singh,
Vineet Kumar,
Nazia Rizivi,
Manish Yadav,
Mohammad Kaleem Ahmad,
Vijay Kumar,
Abbas Ali Mahdi
Publication year - 2017
Publication title -
turkish journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 27
eISSN - 1303-6165
pISSN - 1300-0144
DOI - 10.3906/sag-1509-4
Subject(s) - exon , osteosarcoma , missense mutation , medicine , osteochondroma , cyr61 , gene , cancer research , malignancy , genetics , mutation , pathology , biology , ctgf , anatomy , growth factor , receptor
Osteosarcoma requires an angiogenesis process. CYR61 is one of the extracellular signaling molecules that promote angiogenesis, tumor growth, and the malignancy of osteosarcoma. In the present study, we investigate the CYR61 gene variations in osteosarcoma and their correlations with clinicopathological findings.

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